Description
Vasoactive Intestinal Peptide (VIP) is a naturally occurring 28–amino acid neuropeptide known for its broad biological roles across both the nervous system and peripheral tissues. It functions as a signaling molecule with hormone-like and neurotransmitter-like activity, contributing to regulation of multiple physiological systems.
VIP primarily exerts its effects through interaction with specific receptors including VPAC1 and VPAC2, which are G-protein coupled receptors. Activation of these receptors stimulates adenylyl cyclase, leading to increased intracellular cAMP levels and downstream signaling involved in smooth muscle relaxation and systemic regulation.
In research models, VIP is widely studied for its diverse functional activity, including pathways related to vasodilation, bronchodilation, gastrointestinal regulation, and immune modulation. Due to its widespread receptor distribution and multi-system activity, VIP continues to be an important compound in investigations of neuropeptide signaling and integrative physiology.
Research applications include investigation of:
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neuropeptide signaling pathways and receptor activity
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cardiovascular regulation and vasodilation mechanisms
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gastrointestinal physiology and motility control
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respiratory function and bronchodilation pathways
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immune response modulation and inflammatory signaling
For research use only.
Ensure research chemical potency with VIP peptide.
- guaranteed purity
- third-party tested
- sterilized vials
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