Description
GHK-Cu is a naturally occurring copper peptide complex formed when the tripeptide glycine–histidine–lysine (GHK) binds with copper ions (Cu²⁺). This biologically active complex was first identified in human plasma and has since become widely studied in research focused on tissue repair, wound healing, and regenerative signaling.
The copper ion is coordinated primarily through binding sites within the histidine and lysine residues, creating a stable copper-chelated structure. This copper binding is considered essential, as it contributes to the compound’s functional profile and is associated with stronger biological activity compared to GHK alone.
In laboratory models, GHK-Cu has been investigated for multiple repair-related mechanisms, including stimulation of collagen-related pathways, regulation of matrix metalloproteinase (MMP) activity, and support of angiogenesis involved in tissue remodeling. Due to its broad influence on cellular signaling, it has also been explored for effects on cell proliferation, extracellular matrix organization, and overall regenerative biology processes.
Research applications include investigation of:
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wound healing and tissue remodeling mechanisms
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regenerative biology signaling pathways
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collagen and extracellular matrix regulation
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tissue engineering research models
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copper-dependent cellular repair processes
For research use only.
Firm Foundation Peptides’ GHK-Cu peptide is available in 50mg and 100mg.
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